Research Results in Pharmacology 2(1): 58-62, doi: 10.18413/2313-8971-2016-2-1-58-62
TEST-SYSTEM FOR ESTIMATION OF ACTIVITY OF GSK-3 INHIBITORS AS ANTIHYPOXANTS AND DIFFERENTIATION OF ENDOTHELIAL PROGENITORS IN VITRO
expand article infoYouri E. Burda, Sergey V. Nadezhdin, Ekaterina V. Zubareva, Mikhail Vladimirovich Pokrovskii, Alexander V. Faitelson, Svetlana Burda, Maria S. Shirina
Open Access
Abstract
A model test-system was developed for validation in vitro of antihypoxic and endothelio-differentiating activity of newly created glycogen synthase kinase-3 inhibitors in comparison with the reference drug β4-thymosin.
Keywords
glycogen synthase kinase-3, GSK-3, β4-thymosin, hypoxia, ischemia, endothelium.