Research Article
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Article title
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Abstract
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Keywords
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Introduction
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Materials and methods
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Experimental animals
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Chemicals and drugs
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Synthesis of acexazolamide
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Drug administration
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Acute toxicity evaluation
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Ulcerogenic activity
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Acute ulcerogenic activity
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Subchronic ulcerogenic activity
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Anti-inflammatory activity
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Formalin-induced edema
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Cotton pellet granuloma
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Analgesic activity
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Acetic acid-induced abdominal constrictions
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Hot-plate model
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Randall & Selitto test (paw-pressure test)
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Antipyretic activity
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Active Cutaneous Anaphylactic (ACA) Reactions
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Anti-burn activity
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Determination of acexazolamide in blood plasma by HPLC-MS/MS method
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Evaluation of bioavailability
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Statistical analysis methods
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Results and discussion
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Acute toxicity
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Ulcerogenic activity
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Acute ulcerogenic activity
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Subchronic ulcerogenic activity
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Anti-inflammatory activity
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Formalin-induced edema
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Cotton pellet granuloma
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Analgesic activity
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Model of mechanic irritation of inflammatory paw edema (Randall & Selitto test)
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Abdominal constriction test induced by acetic acid (writhings)
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Hot-plate model
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Antipyretic activity
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Antiallergic activity
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Anti-burn activity
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Bioavailability of acexazolamide
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Conclusion
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Acknowledgements
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References
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Author contributions